Increased inflammation, disturbed extracellular matrix remodeling and reduced parotid and submandibular salivary gland function in male Wistar rats with type 2 diabetes

Key Points

• The research aims to understand how inflammation affects salivary gland function in the context of type 2 diabetes.
• Utilized male Wistar rats as the experimental model.
• Assessed levels of salivary inflammatory biomarkers.
• Evaluated salivary secretory function.
• Monitored changes in extracellular matrix remodeling.
• Identified increased levels of salivary inflammatory biomarkers.
• Observed decreased salivary secretory function.
• Noted significant impairment in parotid and submandibular gland function.