There is ongoing scientific and societal discourse on the definition of biological sex. At this critical moment when misinformation about sex is being applied to policy globally, scientific clarification is valuable. Here, we evaluate the primary approaches to defining sex and synthesise the active discourse to conclude that there is no current consensus on a definition of sex that is free of assumptions and limitations. While there is no current consensus, we do not advocate for a single definition and contend that a lack of unanimity is not inherently problematic. No matter what definitional choices are used, we provide actionable recommendations to improve accuracy when describing sex. Most importantly, regardless of scientific debates, no biological definition of sex should be used to dictate human rights.
Eppley et al. (Sun,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: