Eligibility for Anti-Amyloid-β Monoclonal Antibodies in Patients With Primary Progressive Aphasia due to Alzheimer's Disease in Japan.

Key Points

• The central aim is to determine how SPECT imaging can aid in distinguishing between language-predominant Alzheimer's disease and other types of primary progressive aphasia.
• Examined the role of SPECT imaging in diagnosis.
• Focused on patients with language-predominant symptoms.
• Compared cases of language variant Alzheimer's disease (lvAD) with primary progressive aphasia (PPA).
• SPECT may effectively support differentiation between lvAD and PPA.
• Accurate identification of lvAD is critical for appropriate treatment options.