Comparing Surrogate Indexes for Insulin Resistance as Predictors of Type 2 Diabetes (T2D) | Synapse
March 13, 2026Open Access
Comparing Surrogate Indexes for Insulin Resistance as Predictors of Type 2 Diabetes (T2D)
Key Points
This research aims to identify which surrogate measures of insulin resistance best predict the onset of type 2 diabetes (T2D).
Comparison of surrogate measures based on Oral Glucose Tolerance Tests (OGTTs) and fasting insulin levels.
Analysis of predictive performance of each measure for T2D diagnosis.
Surrogate measures based on OGTTs are the most effective in predicting T2D.
Fasting insulin measures outperform those that do not account for insulin.
Abstract
Surrogate measures based on OGTTs are best for predicting T2D, while measures based on fasting insulin perform better than those that do not measure insulin.