What question did this study set out to answer?

To identify the role of proteinuria as a predictor of residual kidney function loss in hemodialysis patients.

March 15, 2026Nephrology Dialysis Transplantation0 citations

The deleterous effect of proteinuria in residual kidney function in hemodialysis patients

BÁBeatriz Sánchez ÁlamoInstituto Cajal IMIrene MinguezInstituto Cajal MDMartha Elisabeth Díaz DomínguezInstituto Cajal

Key Points

To identify the role of proteinuria as a predictor of residual kidney function loss in hemodialysis patients.
Assess nephrotic-range proteinuria at online-HDF initiation
Evaluate the association with residual kidney function loss
Analyze progression to anuria and β2-microglobulin levels
Proteinuria is an independent predictor of accelerated RKF loss
Elevated β2-microglobulin supports its role as a prognostic marker
Early identification of high-proteinuria patients may enhance preservation strategies for RKF

Abstract

Nephrotic-range proteinuria at online-HDF initiation is an independent predictor of accelerated RKF loss, including progression to anuria. Its association with elevated β2-microglobulin supports its value as a prognostic marker. Early identification of high-proteinuria patients may enable personalized strategies to preserve RKF and improve outcomes.

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