Carbene Intermediates from 1-Methylimidazole and Acylphenylacetylenes in Reaction with Elemental Sulfur: One-Pot Assembly of Functionalized Imidazole-2-thiones

Key Points

• The aim is to develop a method for synthesizing functionalized imidazole-2-thiones from carbene intermediates.
• One-pot synthesis method employed
• Carbene generated from 1-methylimidazole and acylphenylacetylenes
• Elemental sulfur used to intercept the carbene
• Functionalized 1-alkenyl-3-methylimidazole-2-thiones synthesized
• Yields achieved up to 30%