AortaExplorer accurately extracted aortic diameters and tortuosity from over 10,000 CTA scans, reducing analysis time from approximately 15 minutes to under 5 minutes per case.
Observational (n=12,562)
No
Does AortaExplorer accurately and efficiently measure aortic diameters and tortuosity in CTA scans compared to manual expert readings?
AortaExplorer is a highly accurate, time-saving AI tool for automated extraction of aortic biomarkers from CTA scans, enabling large-scale reproducible research.
We introduce AortaExplorer, an open-source, fully automated AI-driven framework for end-to-end aortic analysis from computed tomography angiography (CTA) scans. AortaExplorer extracts established biomarkers, such as diameters across anatomical segments, and introduces novel metrics, including aortic tortuosity. Diameter measurements were validated against expert manual readings in more than 10,000 CTA scans from Danish population cohorts, demonstrating high accuracy. The computed descending aortic tortuosity index aligns with trends reported in previous studies, confirming its increase with age. By reducing analysis time from approximately 15 minutes per case to under five minutes, AortaExplorer enables efficient, reproducible assessment of aortic morphology at scale. This tool supports clinical research and large cohort studies by combining state-of-the-art segmentation performance with extensive visualization and quantitative reporting.
Paulsen et al. (Mon,) conducted a observational in Aortic diseases (n=12,562). AortaExplorer (AI-driven analysis) vs. Manual expert readings was evaluated on Accuracy of automated aortic diameter measurements compared to manual readings. AortaExplorer accurately extracted aortic diameters and tortuosity from over 10,000 CTA scans, reducing analysis time from approximately 15 minutes to under 5 minutes per case.