Abstract Aim: To evaluate and compare the effect of FluoroDip Bioactive, Ultra EZ, and Dente 91 toothpaste on the surface microhardness of enamel following in-office bleaching with 35% hydrogen peroxide. Materials and Methods: Forty extracted human incisor teeth were prepared and randomly divided into four groups (n=10). Baseline enamel surface microhardness was recorded using a Vickers hardness tester. All specimens underwent in-office bleaching with 35% hydrogen peroxide. Group 1 received no remineralizing agent, Group 2 was treated with FluoroDip Bioactive varnish, Group 3 with Ultra EZ gel, and Group 4 with Dente 91 toothpaste. After treatment, specimens were stored in distilled water for 14 days, following which post-treatment microhardness was measured. Statistical analysis was performed using appropriate tests with significance set at p<0.05. Results: Baseline microhardness values showed no statistically significant differences among groups (p=0.32). Post-treatment results demonstrated a significant difference between groups (p<0.001). Group 1 showed a significant reduction in enamel microhardness. Group 2 showed minimal recovery, while Groups 3 and 4 demonstrated significant increases in microhardness, with Dente 91 exhibiting the highest values. Conclusion: In-office bleaching with 35% hydrogen peroxide significantly reduces enamel microhardness. Post-bleaching application of remineralizing agents improves enamel hardness, with Dente 91 showing superior remineralization, followed by Ultra EZ and FluoroDip Bioactive
International Journal of Dental Science and Innovative Research (IJDSIR) (Fri,) studied this question.