A comparison and evaluation of statistical methods for mediation analysis with mixtures of environmental exposures

Key Points

• The aim is to evaluate various statistical methods suitable for mediation analysis involving mixtures of environmental exposures.
• Compared multiple statistical approaches for mediation analysis.
• Assessed each method's strengths based on different data characteristics.
• Provided guidance on method selection according to research goals.
• Identified key strengths and limitations of each statistical method.
• Outlined optimal methods based on specific data features and study aims.