Hydroxychloroquine‐Use and Preeclampsia and Preterm Delivery Complications in Systemic Lupus Erythematosus Pregnancies: Is there a protective effect? | Synapse
March 25, 2026
Hydroxychloroquine‐Use and Preeclampsia and Preterm Delivery Complications in Systemic Lupus Erythematosus Pregnancies: Is there a protective effect?
Key Points
The aim is to evaluate whether hydroxychloroquine use during early pregnancy reduces risks of preeclampsia and preterm delivery in patients with systemic lupus erythematosus.
Analyzed early pregnancy hydroxychloroquine use in systemic lupus erythematosus patients.
Assessed associations with preeclampsia and preterm delivery risks.
Highlighted the need for larger cohort studies to further investigate correlations.
Early pregnancy hydroxychloroquine use was not significantly linked to lower preeclampsia risk.
No significant association was found between hydroxychloroquine and preterm delivery complications.
Abstract
Early pregnancy HCQ-use in SLE patients was not significantly associated with reduced risk of preeclampsia or preterm delivery. Further studies with larger cohorts are needed to clarify these associations.