Abstract Background: We describe the first pediatric case of a 20-month-old female with Sanjad-Sakkati Syndrome who developed acute liver failure with associated multisystem inflammatory syndrome in children МІS-C and a good outcome. The primary finding in this case, is that despite the high morbidity and mortality rates of SSS patients due to its immunosuppressive effects, early aggressive approach to treating severe viral infections manifestations, for instance acute liver failure could lead to a favourable outcome and avoid the need for liver transplant.
Abdulaziz et al. (Sun,) studied this question.