Multidimensional interventions combining personalized pharmacotherapy, physical measures like abdominal compression bands, recumbent exercise training, and family-centered psychosocial support effectively manage reversible autonomic dysregulation in pediatric orthostatic intolerance.
Highlights the conceptual differences between the Japanese diagnosis of orthostatic dysregulation and international OI/PoTS classifications in pediatric patients.
起立不耐症（OI）は，体位性頻脈症候群（PoTS）を含む多因子的な疾患であり，思春期の小児において起立や通学を困難にする．日本では小児起立不耐症は「起立性調節障害（OD）」として診断されるが，この概念は国際的に定義されたOI/PoTS分類と必ずしも一致しない．そのため，国際的な報告の際には，ODのサブタイプを世界的なOI/PoTS分類に対応付けて整理する必要がある．ODは日本の学校欠席の約10%を占める．
Takeuchi et al. (Thu,) conducted a review in Orthostatic intolerance and postural orthostatic tachycardia syndrome. Multidimensional management (pharmacotherapy, physical measures, exercise therapy, psychosocial support) was evaluated. Multidimensional interventions combining personalized pharmacotherapy, physical measures like abdominal compression bands, recumbent exercise training, and family-centered psychosocial support effectively manage reversible autonomic dysregulation in pediatric orthostatic intolerance.