Lan enzyme-free construction of lanthionine-bridged macrocyclic phage libraries

Key Points

• This research aims to develop a method for constructing phage displayed lanthipeptide libraries without the use of Lan enzymes.
• Utilization of phage display technology
• Construction of lanthipeptide libraries
• Elimination of the need for Lan enzymes
• Successful creation of lanthipeptide libraries
• Demonstration of the feasibility of enzyme-free methods
• Establishment of a new approach for macrocyclic phage libraries