Osteogenic effect of platelet-rich fibrin on a bone defect model of long bone in rabbits

Key Points

• The aim is to evaluate the osteogenic properties of platelet-rich fibrin in a bone defect model in rabbits.
• Animal model of long bone defects in rabbits
• Application of platelet-rich fibrin in the defect sites
• Assessment of bone healing after treatment
• Platelet-rich fibrin promoted enhanced bone regeneration in the defect areas
• Significant increase in bone density observed compared to controls
• Improved healing time noted with platelet-rich fibrin application