Endoscopic–Histologic Discordance in Colorectal Small‐Cell Neuroendocrine Carcinoma: The Need for Deep Biopsies

Key Points

• The research aims to investigate the discrepancies between endoscopic findings and histological results in colorectal small-cell neuroendocrine carcinoma.
• Reviewed endoscopic features suggestive of malignancy.
• Assessed histological results from superficial biopsies.
• Evaluated the necessity of deep biopsies for accurate diagnosis.
• Superficial biopsies often misrepresent the presence of malignancy.
• Deep biopsies provide more accurate histological evaluations.
• Multidisciplinary evaluations are crucial for effective diagnosis and treatment.