What question did this study set out to answer?

To explore a microneedle system with a photoactive backing for effective drug delivery to skin wounds.

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April 1, 2026Open Access

A Microneedle with Photoactive Electrospun Backing Layer Enables Multitherapy and Combined Drug Delivery to the Skin Wound

Key Points

To explore a microneedle system with a photoactive backing for effective drug delivery to skin wounds.
Developed a microneedle with a photoactive electrospun layer.
Assessed the ability for multitherapy in wound healing.
Analyzed effectiveness of drug delivery in various skin wound models.
Improved healing observed in test subjects using the microneedle system.
Increased drug absorption and reduced infection rates noted.
Demonstrated potential for simultaneous treatment of multiple wound barriers.

Abstract

Skin wound healing is frequently impaired by infection, inflammation, insufficient vascularization, and chronic pathological conditions, highlighting the need for therapeutic strategies that can address multiple barriers simultaneously. In this study,...

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