Abstract Background: Acute pancreatitis (AP) remains one of the most frequent gastrointestinal causes for hospital admission worldwide. Despite advancements in imaging and supportive care, the management of severe cases continues to pose significant clinical challenges. Objective: This study intends to investigate current diagnostic criteria, severity stratification, and management protocols for acute pancreatitis, comparing international standards with specific regional practices. Methods: A comprehensive literature review was conducted using databases including PubMed, Google Scholar, and WHO guidelines. Data collection focused on studies and clinical protocols published between 2016 and 2026. Inclusion criteria focused on randomized controlled trials, systematic reviews, and national health guidelines from India and Central Asia (Kyrgyzstan). Results: The study identified that while the Atlanta Classification is universally accepted for diagnosis, significant variations exist in the timing of enteral nutrition and the use of prophylactic antibiotics. Regional data shows a higher incidence of biliary pancreatitis in certain demographics, with varying access to early ERCP (Endoscopic Retrograde Cholangiopancreatography).
Kaiypov et al. (Mon,) studied this question.