Extract Lung transplantation (LTx) is now a widely accepted procedure for end-stage pulmonary diseases. Nevertheless, long-term survival after LTx remains limited because of chronic lung allograft dysfunction (CLAD), which is mainly manifested as bronchiolitis obliterans syndrome (BOS), accounting for approximately 80% of CLAD cases 1. The definition of BOS was first introduced in 1993 by an ad hoc working group of the International Society of Heart and Lung Transplantation (ISHLT), with the aim of developing a clinically applicable and standardised method for assessing functional results after LTx 2.
Brugière et al. (Wed,) studied this question.