Editorial Note: Endoplasmic reticulum stress-induced autophagy provides cytoprotection from chemical hypoxia and oxidant injury and ameliorates renal ischemia-reperfusion injury

Key Points

• The aim is to explore the protective role of endoplasmic reticulum stress-induced autophagy in renal injuries caused by chemical hypoxia and oxidants.
• Review of current literature on autophagy and renal protection
• Discussion of mechanisms of ER stress and its impacts on cell survival
• Endoplasmic reticulum stress-induced autophagy enhances cell survival under chemical hypoxia
• Protective effects observed against oxidant injuries and renal ischemia-reperfusion injury