February 21, 2013Open Access
View Full PaperCardiac Output Response to Exercise in Relation to Metabolic Demand in Heart Failure with Preserved Ejection Fraction
Structured PICO
P
Population
Patients with Heart Failure with Preserved Ejection Fraction (HFpEF)
In HFpEF, reduced exercise capacity is primarily driven by inadequate cardiac output relative to metabolic demand rather than just diastolic dysfunction.
Abstract
While diastolic dysfunction promotes congestion and pulmonary hypertension with stress in HFpEF, reduction in exercise capacity is predominantly related to inadequate CO relative to metabolic needs.
Cite This Study
Abudiab et al. (Thu,) studied this question.