Does intravenous amiodarone or coronary revascularization suppress or prevent polymorphous ventricular tachycardia in patients with acute myocardial infarction?
Intravenous amiodarone and coronary revascularization are effective strategies for managing post-myocardial infarction polymorphous ventricular tachycardia, which is often driven by recurrent ischemia.
Post-myocardial infarction polymorphous ventricular tachycardia is not consistently related to an abnormally long QT interval, sinus bradycardia, preceding sinus pauses, or electrolyte abnormalities. This arrhythmia has a variable response to class I antiarrhythmics but may be suppressed by intravenous amiodarone therapy. It is often associated with signs or symptoms of recurrent myocardial ischemia. Furthermore, coronary revascularization appears to be effective in preventing the recurrence of polymorphous ventricular tachycardia when associated with recurrent postinfarction angina.
Wolfe et al. (Tue,) studied this question.