Is P2Y12 inhibitor monotherapy directly following PCI feasible and safe in patients with NSTE-ACS?
First-in-human evidence demonstrates the feasibility and safety of direct P2Y12 inhibitor monotherapy after PCI in NSTE-ACS patients, highlighting the need for future randomized controlled trials.
This study provides first-in-human evidence that P2Y12 inhibitor monotherapy directly following PCI for NSTE-ACS is feasible, without any overt safety concerns, and highlights the need for randomised controlled trials comparing direct P2Y12 inhibitor monotherapy with the current standard of care.
Sangen et al. (Mon,) studied this question.