Single‐Nucleus Transcriptomes of Lacrimal Gland Adenoid Cystic Carcinoma With Different Growth Patterns

Key Points

• The research aims to explore how transcriptional factors influence the growth patterns of lacrimal gland adenoid cystic carcinoma.
• Analyzed single-nucleus transcriptomes from lacrimal gland carcinoma samples.
• Examined the expression of key transcriptional factors and their associated ligands and receptors.
• Evaluated signaling cascades involved in cellular differentiation.
• Identified overexpression of key ligands and receptors related to transcriptional factors.
• Revealed dysregulated signaling cascades impacting cellular differentiation.
• Suggested a state of developmental ambiguity in certain growth patterns.