June 30, 2023Open Access

Inhibition of DRP1-dependent mitochondrial fission by Mdivi-1 alleviates atherosclerosis through the modulation of M1 polarization

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Abstract

Inhibition of DRP1-dependent mitochondrial fission by Mdivi-1 alleviated atherogenesis via suppressing mito-ROS/NLRP3-mediated M1 polarization, indicating DRP1-dependent mitochondrial fission as a potential therapeutic target for AS.

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Su et al. (Fri,) studied this question.

synapsesocial.com/papers/69d6eb198dca315383ed94fe https://doi.org/https://doi.org/10.1186/s12967-023-04270-9

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