Preclinical and Early Clinical Profile of a Highly Selective and Potent Oral Inhibitor of Aldosterone Synthase (CYP11B2)

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Characterization of Two Genes Encoding Human Steroid 11β-Hydroxylase (P-45011β)1989 · 399 citations
2. 2[Late phase II study of CGS16949A, a new aromatase inhibitor--a multicentral cooperative study (Western Japan Group)].1994 · 2 citations
3. 3The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism2011 · 55 citations
4. 4Eplerenone2005 · 35 citations
5. 5Mineralocorticoid receptor knockout mice: Pathophysiology of Na ⁺ metabolism1998 · 411 citations