Efficacy of Prophylactic Tranexamic Acid in Preventing Postpartum Hemorrhage after Vaginal Delivery: Evidence from a Randomized Controlled Study | Synapse
April 10, 2026
Efficacy of Prophylactic Tranexamic Acid in Preventing Postpartum Hemorrhage after Vaginal Delivery: Evidence from a Randomized Controlled Study
Key Points
The study aims to evaluate the effectiveness of tranexamic acid in conjunction with oxytocin for preventing postpartum hemorrhage after vaginal delivery.
Conducted a randomized controlled trial
Compared the use of oxytocin alone versus oxytocin with tranexamic acid
Measured outcomes related to postpartum hemorrhage and blood loss
Oxytocin combined with tranexamic acid significantly reduced postpartum hemorrhage
Minimized overall blood loss compared to oxytocin alone
Abstract
The findings of our study indicate that the use of oxytocin with TXA is more effective in preventing PPH and minimizing blood loss compared to oxytocin alone.