What is the clinical evidence from this study?

Study design: Case Report. Population: Hb Quong Sze Co-Inherited Thai Deletion with Falsely Elevated HbA1c (n=1).

What question did this study set out to answer?

The aim is to explore how Hb QS-H disease affects the measurement of HbA1c levels.

April 10, 2026

A Case of Hb Quong Sze Co-Inherited Thai Deletion Resulting in Falsely Elevated HbA1c Values

Key Result

Co-inheritance of Hb Quong Sze and Thai deletion can result in falsely elevated HbA1c values.

Key Points

The aim is to explore how Hb QS-H disease affects the measurement of HbA1c levels.
Analyzed the impact of Hb QS-H on HbA1c levels
Compared results across various detection platforms
Observed methodological variability in HbA1c quantification
Significant interference with HbA1c measurement due to Hb QS-H
Variability in quantification results across different detection platforms

Study Design

Type

Case Report (n=1)

Structured PICO

Does Hb QS-H disease interfere with HbA1c quantification across different detection platforms?

Population

A patient with Hb Quong Sze Co-Inherited Thai Deletion (Hb QS-H disease)

Intervention

HbA1c quantification using different detection platforms

Outcome

Interference with HbA1c quantification (falsely elevated values)surrogate

Clinicians should be aware that Hb QS-H disease can cause falsely elevated HbA1c values, highlighting the need to consider hemoglobinopathies when HbA1c does not match the clinical picture.

Abstract

Our findings demonstrate that Hb QS-H disease significantly interferes with HbA1c quantification, with methodological variability observed across different detection platforms.

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Discussion

Cite this study

Wei et al. (Thu,) conducted a case report in Hb Quong Sze Co-Inherited Thai Deletion with Falsely Elevated HbA1c (n=1). Co-inheritance of Hb Quong Sze and Thai deletion can result in falsely elevated HbA1c values.

synapsesocial.com/papers/69d894526c1944d70ce053d4 — DOI: https://doi.org/10.7754/clin.lab.2025.250573

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Authors

Qianqing Wei

Liang Liang

Zugui Li

Journals

Clinical Laboratory

Actions

References and Citations

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Analyzing shared references across papers

A Case of Hb Quong Sze Co-Inherited Thai Deletion Resulting in Falsely Elevated HbA1c Values

Key Result

Key Points

Study Design

Structured PICO

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Authors

Journals

Actions

References and Citations

Citation Network

Connected Papers

Discussion

Also consider