Does ezetimibe monotherapy improve lipid and lipoprotein levels in people with hypercholesterolaemia?
Ezetimibe monotherapy provides favorable short-term changes in lipid profiles for patients with hypercholesterolemia.
In a meta-analysis restricted to short-term trials in hypercholesterolaemia, significant potentially favourable changes in lipid and lipoprotein levels relative to baseline occurred with ezetimibe monotherapy. Further long-term studies with cardiovascular and other clinical outcome data are needed to assess the efficacy and safety of ezetimibe more fully.
Pandor et al. (Tue,) studied this question.