December 12, 2012Open Access

Prognostic Significance of Progesterone Receptor–Positive Tumor Cells Within Immunohistochemically Defined Luminal A Breast Cancer

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Abstract

Semiquantitative IHC expression of PR adds prognostic value within the current IHC-based luminal A definition by improving the identification of good outcome breast cancers. The new proposed IHC-based definition of luminal A tumors is HR positive/HER2 negative/Ki-67 less than 14%, and PR more than 20%.

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Prat et al. (Wed,) studied this question.

synapsesocial.com/papers/69d901e2d2f7327e70ae4c43 https://doi.org/https://doi.org/10.1200/jco.2012.43.4134

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