April 19, 2023Open Access

Towards a consensus definition of allostatic load: a multi-cohort, multi-system, multi-biomarker individual participant data (IPD) meta-analysis

Structured PICO

Population

Participants in multiple cohorts (individual participant data)

Intervention

5-item measure of allostatic load (AL) and peak expiratory flow (PEF)

Outcome

Identification of a consensus definition and set of biomarkers for allostatic loadsurrogate

Identified a 5-item measure of allostatic load and PEF as efficient biomarkers for capturing physiological wear and tear.

Abstract

This study has identified a brief 5-item measure of AL that arguably represents a universal and efficient set of biomarkers for capturing physiological 'wear and tear' and a further biomarker (PEF) that could usefully be included in future data collection.

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Cite This Study

McCrory et al. (Wed,) studied this question.

synapsesocial.com/papers/69d91ae6ccb0bba5a568416a https://doi.org/https://doi.org/10.1016/j.psyneuen.2023.106117

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