Cerebral Cortex Activation during Experimentally Induced Ventilator Fighting in Normal Humans Receiving Noninvasive Mechanical Ventilation

This study indicates that "ventilator fighting" in healthy humans is associated with an activation of higher cerebral areas. Premotor potentials could thus be markers of patient-ventilator asynchrony at the brain level. Both corroboration in patients and the elucidation of the causative or reactive nature of the association are needed before determining clinical implications.