December 23, 2021

How to best monitor bivalirudin anticoagulant effect for ECMO and VAD—Comparison of four assay methods

Does the dTT1:10 assay provide better monitoring of bivalirudin anticoagulant effect compared to other assay methods in pediatric ECLS?

Population

Pediatric patients on extracorporeal life support (ECLS), including ECMO and VAD, receiving bivalirudin

Intervention

dTT1:10 assay method for monitoring bivalirudin

Comparator

Three other assay methods

Outcome

Suitability for routine practice (assay variations and cost)surrogate

The dTT1:10 assay is recommended for routine monitoring of bivalirudin in pediatric ECLS due to its reliability and cost-effectiveness.

dTT1:10 appears to be more suitable for routine practice due to fewer variations and lower cost for monitoring bivalirudin in pediatric ECLS.

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Cite This Study

Teruya et al. (Thu,) studied this question.

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