Magnetic ResonanceImages Implicate That Glymphatic Alterations Mediate Cognitive Dysfunction inAlzheimer Disease

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Abstract

Glymphatic system activity may act as a significant mediator in AD-related cognitive dysfunction even after adjusting for multiple covariates and gray matter volumes. ALPS-index may provide useful disease progression or treatment biomarkers for patients with AD as an indicator of modulation of glymphatic activity. ANN NEUROL 2023;93:164-174.

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Discussion

Journals

Annals of Neurology

Institutions

National Yang Ming Chiao Tung University

Chang Gung University

Chang Gung Memorial Hospital

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