Geographical distribution of Mycobacterium tuberculosis complex lineages in sub-Saharan Africa: An interactive review.

Key Points

• To assess the ability of sub-Saharan African countries to monitor Mycobacterium tuberculosis genomic changes over 25 years.
• Examined genomic data from 49 countries in sub-Saharan Africa
• Analyzed a total of 8141 GenBank entries
• Included 163 unreported whole genome sequences from a specific institute
• Sub-Saharan Africa accounts for 85% of tuberculosis cases in Africa
• Diverse lineages of Mycobacterium tuberculosis were identified
• Genomic monitoring capabilities vary significantly across countries