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Hereditary angioedema is a rare genetic disease that may include recurrent attacks of cutaneous angioedema, severe abdominal pain, and airway compromise. Prophylaxis and treatment include C1 inhibitor replacement and inhibition of the kallikrein and bradykinin pathways.
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Paula J. Busse
Witten/Herdecke University
Sandra C. Christiansen
La Jolla Institute for Immunology
New England Journal of Medicine
University of California, San Diego
Icahn School of Medicine at Mount Sinai
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Busse et al. (Wed,) studied this question.
synapsesocial.com/papers/69dc24474ee46a2379b65152 — DOI: https://doi.org/10.1056/nejmra1808012