September 17, 2019Open Access

Which Multicenter Randomized Controlled Trials in Critical Care Medicine Have Shown Reduced Mortality? A Systematic Review

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Abstract

A systematic literature search provided no conclusive evidence of any pharmacologic intervention that has consistently reduced mortality in critically ill patients. Strategies associated with improved or noninvasive mechanical ventilation were associated with reduced mortality.

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Santacruz et al. (Tue,) studied this question.

synapsesocial.com/papers/69dc39fc3080d3567e274af0 https://doi.org/https://doi.org/10.1097/ccm.0000000000004000

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