Do low levels of urinary albumin excretion predict the incidence of cardiovascular disease events in middle-aged nonhypertensive and nondiabetic individuals?
Low-grade albuminuria (UACR <30 microg/mg) predicts cardiovascular disease events even in nonhypertensive, nondiabetic individuals, challenging the definition of normal albumin excretion.
In our community-based sample of middle-aged nonhypertensive, nondiabetic individuals, low levels of urinary albumin excretion well below the current microalbuminuria threshold predicted the development of CVD. Our observations add to the growing body of evidence that challenges the notion that UACR <30 microg/mg indicates "normal" albumin excretion.
Ärnlöv et al. (Tue,) studied this question.