July 2, 2010Open Access
View Full PaperArterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation
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Abstract
This study provides direct in vivo evidence that in arteries and aortic valves, macrophage burden and calcification associate with each other, whereas inflammation inversely correlates with bone mineralization. Thus, understanding inflammatory signalling mechanisms may offer insight into selective abrogation of divergent calcific phenomena.