PCSK6 is a newly identified protein involved in cardiac remodeling post-myocardial infarction, discovered via mass spectrometry of the primary cardiomyocyte secretome.
A novel mass spectrometry-based approach allows investigation of the secretome of primary cardiomyocytes. Analysis of hypoxia-induced secretion led to the identification of PCSK6 as being crucially involved in cardiac remodeling after acute myocardial infarction.
Kuhn et al. (Wed,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: