Diabetes mellitus is a complex metabolic disorder marked by chronic hyperglycemia and associated with progressive complications affecting multiple organ systems. The limitations of conventional anti-diabetic therapies, including adverse effects and incomplete metabolic control, have driven interest toward holistic and multi-targeted approaches such as Ayurveda. ManahVeda Diabohealth (DH) Tablets are an Ayurvedic proprietary polyherbal formulation developed to support glycemic regulation and metabolic balance through synergistic herbal actions. The formulation contains standardized extracts of Momordica charantia (Karela), Gymnema sylvestre (Gudmar), Syzygium cumini (Jamun), Trigonella foenum-graecum (Fenugreek), Cinnamomum zeylanicum (Cinnamon), Pterocarpus marsupium (Vijaysar), Swertia chirata (Chirayata), Emblica officinalis (Amla), Withania somnifera (Ashwagandha), and Asphaltum punjabianum (Shilajit). These herbs are traditionally recognized for their antihyperglycemic, insulin-sensitizing, antioxidant, anti-inflammatory, and pancreatic protective properties. The therapeutic rationale of Diabohealth Tablets lies in their multi-mechanistic action, including enhancement of insulin secretion, improvement of peripheral glucose uptake, modulation of carbohydrate metabolism, reduction of oxidative stress, and restoration of metabolic homeostasis. From an Ayurvedic perspective, the formulation aids in correcting Agni dysfunction, balancing Kapha and Vata doshas, and addressing the pathophysiology of Madhumeha at both systemic and cellular levels. In addition to glycemic control, the formulation may contribute to improved energy levels, stress modulation, and overall quality of life. Collectively, ManahVeda Diabohealth Tablets represent a rational Ayurvedic intervention for integrative diabetes management. However, well-designed clinical studies are necessary to validate their long-term efficacy, safety, and therapeutic outcomes. Keywords: Diabetes mellitus; Ayurvedic medicine; Polyherbal formulation; Glycemic control; Madhumeha; ManahVeda Diabohealth Tablets
Khan et al. (Wed,) studied this question.