Biologics for chronic rhinosinusitis with nasal polyps: a real-world prospective cohort study.

Key Points

• The study aims to assess the real-world efficacy of biologics in treating chronic rhinosinusitis with nasal polyps (CRSwNP).
• Conducted a real-world prospective cohort analysis
• Included patients with severe chronic rhinosinusitis with nasal polyps
• Evaluated the clinical benefits of three registered biologics
• Significant clinical benefit observed with all three biologics
• Larger improvements noted in patients treated with dupilumab