What question did this study set out to answer?

The aim is to investigate how temporary ion-pairing between lecithin and glycolic acid improves exfoliation in a biphasic serum.

April 18, 2026

Shake‐Induced Temporary Ion‐Pairing Between Lecithin and Glycolic Acid for Enhanced Exfoliation in a Novel Biphasic Serum: Comparative Ex Vivo and in Vivo Randomised Studies

Key Points

The aim is to investigate how temporary ion-pairing between lecithin and glycolic acid improves exfoliation in a biphasic serum.
Conducted ex vivo and in vivo randomized studies
Tested the efficacy of the biphasic serum
Compared safety profiles against traditional formulations
Enhanced exfoliation efficacy observed compared to standard glycolic acid systems
Superior safety profile reported for consumer applications
Temporary ion-pairing effectively overcomes pH-dependent limitations of glycolic acid

Abstract

The biphasic system successfully overcomes pH-dependent limitations of glycolic acid through temporary ion-pairing, providing enhanced exfoliation efficacy with a superior safety profile for consumer applications.

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Cite This Study

Kwon et al. (Wed,) studied this question.

synapsesocial.com/papers/69e321aa40886becb6540b7d https://doi.org/https://doi.org/10.1111/srt.70349

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Discussion

Journals

Skin Research and Technology

Institutions

Samjin Pharm (South Korea)

References and Citations

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Shake‐Induced Temporary Ion‐Pairing Between Lecithin and Glycolic Acid for Enhanced Exfoliation in a Novel Biphasic Serum: Comparative Ex Vivo and in Vivo Randomised Studies

Key Points

Abstract

Citation Network

Connected Papers

Cite This Study

Also Consider

Discussion

Journals

Institutions

References and Citations

Also Consider