What question did this study set out to answer?

To investigate the long-term outcomes associated with antipsychotic use in young ischemic stroke patients.

April 22, 2026Open Access

Antipsychotics and Their Association With Long‐Term Outcomes in Young Ischemic Stroke Patients

Key Result

Pre-stroke antipsychotic use in young ischemic stroke patients was associated with recurrent vascular events and mortality.

Key Points

To investigate the long-term outcomes associated with antipsychotic use in young ischemic stroke patients.
Analyzed the history of antipsychotic use in young ischemic stroke patients before and after the event
Evaluated the association between antipsychotic use and recurrence of vascular events and mortality
Approximately 6% of young ischemic stroke patients had a history of antipsychotic use
Pre-stroke antipsychotic use correlated with an increased risk of recurrent vascular events and higher mortality rates

Structured PICO

Does antipsychotic use affect recurrent vascular events and mortality in young ischemic stroke patients?

Population

Young ischemic stroke (IS) patients

Intervention

Antipsychotic use (pre-stroke or post-stroke)

Comparator

No antipsychotic use

Outcome

Recurrent vascular events and mortalityhard clinical

Pre-stroke antipsychotic use in young ischemic stroke patients is associated with an increased risk of recurrent vascular events and mortality.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Around 6% of young IS patients had a history of antipsychotic use, while a similar proportion initiated antipsychotics post-stroke. Pre-stroke antipsychotic use was associated with recurrent vascular events and mortality.