Dry eye syndrome (DES) is a multifactorial disorder of the ocular surface that can affect work productivity as well as physical and mental health. In recent years, the prevalence of DES has continued to increase among adolescents and young adults, in line with rising digital device use for learning and work activities. This systematic review aims to evaluate the relationship between DES and sleep quality in adolescent and young adult populations. This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Literature searches were performed through PubMed, Science Direct, ProQuest, and Wiley databases. Included studies were observational research published within the past 5 years that examined the association between DES and sleep quality. Data were analyzed using Review Manager version 5.4, and methodological quality assessment was performed using the Newcastle–Ottawa Scale. A total of three cross-sectional studies that met the inclusion criteria were included in this review. The pooled analysis showed a statistically significant association between poor sleep quality and an increased risk of DES (odds ratios = 1.35; 95% confidence interval: 1.06–1.71; P = 0.01). Quality assessment of these three studies indicated risk of bias ranging from low to moderate. Poor sleep quality is associated with an increased risk of DES among adolescents and young adults.
Hamonangan et al. (Wed,) studied this question.