A BSTRACT Background: To analyze the global, regional, and national burden of high body mass index (BMI)-related type 2 diabetes from 1990 to 2021 and projections for 2040. Methods: The death and disability-adjusted life years (DALYs) with the corresponding age-standardized rates of high BMI-related type 2 diabetes were analyzed using the Global Burden of Disease 2021. The death and DALYs for 2040 were forecasted with an autoregressive integrated moving average model. Results: Globally, 723,719 (95% uncertainty interval UI: 306,923 to 1,075,367) death cases and 39,309,214 (95% UI: 19,146,834 to 56,417,300) DALYs cases were recorded in 2021. The age-standardized death rate was 8.46 (3.55 to 12.62) per 100,000 population, and the DALYs rate was 452.55 (220.36 to 650.49) per 100,000 population. Compared with those in 1990, the death and DALYs rates increased by 33.75% and 79.92%, respectively. In 2021, Oceania, especially Fiji, had the highest age-standardized death and DALYs rates. The global burden on males was similar to that on females. The age-standardized death rate peaked in the 65–69 age group and DALYs rate in age 60–64 years. Low-middle sociodemographic index regions showed the highest age-standardized death and DALYs rates. By 2040, age-standardized death and DALYs rates were projected to increase by 14.7% and 35.43%, respectively. Conclusion: Global burden is heavy, significant regional, and national disparities remained, which emphasizes the need for targeted interventions.
Guo et al. (Sun,) studied this question.