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April 23, 2026

Anti-inflammatory Effect of Gallic Acid on Chronic Bacterial Prostatitis: Involving Target Tissue Distribution

YHYuhong HuangTianjin University of Traditional Chinese Medicine XLXiaomei LiuTianjin University of Traditional Chinese Medicine SKS.K. KongTianjin University of Traditional Chinese Medicine

Key Points

The research investigates the anti-inflammatory effects of gallic acid on chronic bacterial prostatitis by analyzing its pharmacokinetics and tissue distribution.
Utilized LC-MS/MS to analyze the pharmacokinetics of gallic acid.
Examined target tissue distribution to understand tissue-specific effects.
Assessed the anti-inflammatory properties of gallic acid in a chronic bacterial prostatitis model.
Gallic acid exhibits significant anti-inflammatory effects in the target tissues.
The pharmacokinetic analysis revealed effective distribution of gallic acid to inflamed tissues.
Improvements in inflammatory markers were observed in treated subjects.

Abstract

Gallic acid (GA), also known as 3,4,5-trihydroxybenzoic acid, is a polyphenolic bioactive component in pomegranates, grapes, tea leaves, and gallnuts. This study employed LC-MS/MS to systematically analyze the pharmacokinetic and...

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