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This article aims to examine the significant challenges faced in modern pituitary surgery, especially regarding the sella turcica.

April 24, 2026Open Access

Pituitary Surgery from the Pioneers to Recent Technological Innovations: What are the Key Challenges of 21st Century Surgery of the Sella Turcica?

Key Points

This article aims to examine the significant challenges faced in modern pituitary surgery, especially regarding the sella turcica.
Review of recent literature on surgical techniques for the sella turcica.
Analysis of key challenges like anatomical variability and postoperative complications.
Endoscopic techniques have improved surgical approaches but not eliminated challenges.
Anatomical variability and complications remain significant issues in surgical outcomes.

Abstract

Over the past two decades, surgical approaches to the sella turcica have evolved significantly, particularly with the adoption of endoscopic transsphenoidal techniques.Despite these advancements, several challenges persist, including anatomical variability, age-related morphological changes, management of large pituitary adenomas, postoperative complications, and technological limitations.This perspective article discusses these key challenges, drawing upon recent literature to highlight areas requiring ongoing research and innovation.

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Pituitary Surgery from the Pioneers to Recent Technological Innovations: What are the Key Challenges of 21st Century Surgery of the Sella Turcica?

Key Points

Abstract

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