Synthesis of 2-aminobenzothiazole substituted indole via DBU catalyzed addition of indole and benzothiazolimine

Key Points

• The aim is to synthesize 2-aminobenzothiazole substituted indoles using a DBU-catalyzed reaction.
• Developed a DBU-catalyzed Mannich reaction between indoles and benzothiazolimines.
• Utilized mild conditions to enhance efficiency and practicality.
• Focused on pharmaceutical applicability of synthesized compounds.
• Successfully synthesized a series of 2-aminobenzothiazole substituted indoles.
• Demonstrated efficiency of the reaction process under mild conditions.