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May 2, 20260 citationsOpen Access

Unified Tripartite Framework for the Origin of Life: Integrating Nonlinear Chemical Diversity, Network Topology, and Non-equilibrium Kinetics

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IMikutoshi miyamoto

Key Points

  • To propose a unified mathematical framework that integrates topological and kinetic models for understanding the origin of life.
  • Developed three mathematical conditions: Diversity Explosion, Information Network Emergence, and Physical Survival of Dissipative Structures.
  • Synthesized graph-theoretical and kinetic models in a conceptual hypothesis for the emergence of early chemical ecosystems.
  • Defined intersections of non-equilibrium thermodynamic conditions with nonlinear chemical diversity.
  • Proposed that the emergence of a chemical ecosystem is a statistical consequence of specific thermodynamic conditions.
  • Identified key intersections of diversity and kinetics necessary for the transition to autonomous life forms, such as the Last Universal Common Ancestor (LUCA).
  • Provided a theoretical basis for coupling topology and kinetics, highlighting their interdependence in the study of life's origins.

Abstract

The origin of life represents a fundamental phase transition from a lifeless chemical soup to an autonomous, information-preserving dissipative structure. Historically, theoretical approaches to this transition have been bifurcated: graph-theoretical models focus on the topological emergence of autocatalytic sets, while kinetic models emphasize the ther- modynamic conditions required for physical survival. This paper proposes three explicit mathematical conditions as a conceptual hypothesis to synthesize these two approaches: (1)Diversity Explosion (Chemical Potential), (2) Information Network Emergence (Topology), and (3) Physical Survival of Dissipative Structures (Kinetics). By defining the intersection of these three conditions, we present a working hypothesis that the emergence of a chemical ecosystem—the precursor to the Last Universal Common Ancestor (LUCA)—is not a singular miraculous event, but a statistical consequence when nonlinear chemical combination intersects with highly localized, non-equilibrium thermodynamic conditions. This framework provides a theoretical basis for mathematically coupling topology and kinetics, which have largely been treated as semi-independent paradigms.

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Cite This Study

ikutoshi miyamoto (2026) studied this question.

synapsesocial.com/papers/69f5952971405d493a00032fhttps://doi.org/10.5281/zenodo.19933308
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