Impact of IL6 and IL10 Genotype on Cytokines and Preeclampsia in a Pregnant Multi-Ethnic Cohort of Women With Overweight and Obesity. | Synapse
May 3, 2026
Impact of IL6 and IL10 Genotype on Cytokines and Preeclampsia in a Pregnant Multi-Ethnic Cohort of Women With Overweight and Obesity.
Key Points
This research investigates how IL6 and IL10 genotypes affect cytokine levels and the risk of preeclampsia in pregnant women.
Analyzed the impact of IL6 and IL10 genotypes on cytokine expression in a multi-ethnic cohort.
Focused on women with overweight and obesity during pregnancy.
Monitored inflammatory markers to assess risks of preeclampsia.
IL6 and IL10 genotypes significantly influenced the levels of anti-inflammatory cytokines.
Findings indicate a strong link between genetic variations and preeclampsia risk in overweight pregnant women.
Cytokine levels correlated with preeclampsia incidence, suggesting a pathway for intervention.
Abstract
genotype may influence circulating anti-inflammatory cytokines across pregnancy and, as such, may contribute to preeclampsia by influencing anti-inflammatory cytokine expression across pregnancy.